Diabetes-associated Phenotypic Masking of Fluoroquinolone Resistance in Multidrug-resistant Tuberculosis: Evidence from Genotypic-Phenotypic Discordance in Surabaya, Indonesia.

Abstract excerpt

BACKGROUND: Emerging fluoroquinolone (FQ) resistance threatens multidrug-resistant tuberculosis (MDR-TB) management, complicating access to shorter regimens. This study characterizes FQ-resistant TB (FQ-R-TB) patients in Surabaya, Indonesia, and assesses diagnostic performance and therapeutic outcomes associated with this resistance. METHODS: A retrospective cohort analysis was conducted using national TB data...

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