Article
Spectrum of common and uncommon compound epidermal growth factor receptor mutations in non-small cell lung carcinoma: An institutional experience from tertiary care centers from Eastern India.
Indian journal of pathology & microbiology - 1 Apr 2026
Sable Mukund N, Mishra Swetasmita, Patra Susama, Mishra Pritinanda, Mahapatra Prashanta R, Majumdar Saroj Das, Mishra Saurav K
Abstract excerpt
BACKGROUND: Non-small cell lung cancer (NSCLC) constitutes about 85% of lung cancer cases. Epidermal growth factor receptor tyrosine kinase inhibitors ( EGFR -TKIs) have improved survival rates in patients with EGFR -sensitizing mutations. Compound mutations in the EGFR gene are infrequent in NSCLC, with an incidence of usually <1%. The objective of this investigation is to identify compound EGFR mutations in...
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