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Article

Clinicopathological and genetic analysis of primary intraosseous carcinoma not otherwise specified (PIOC NOS).

BMC oral health - 29 Jun 2026

Yasuda Sachiko, Oya Kaori, Ikuta Shoko, Takata So, Nakatani Yoichiro, Totoki Yasushi, Uzawa Narikazu, Yachida Shinichi

Abstract excerpt

BACKGROUND: Primary intraosseous carcinoma not otherwise specified (PIOC NOS) is an extremely rare jawbone cancer, accounting for approximately 1-2% of all oral cancers. Considering its rarity, no established standard treatment exists for postoperative recurrence or metastasis. This study aimed to analyse the clinical manifestations of this disease and identify novel genomic abnormalities to aid identification of...

Read the complete abstract on PubMed

Topics

Humans
Female
Male
Jaw Neoplasms
Neoplasm Recurrence, Local
Mutation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

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Identifiers

PMID: 42374478
DOI: 10.1186/s12903-026-09040-9
PMCID: PMC13576325

Genes

PIK3CA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 21 Oct 2026.

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