Computer-guided enzyme engineering of PET hydrolase mutants towards improved PET affinity.

Abstract excerpt

Polyethylene Terephthalate (PET) is an extensively used plastic whose durability and resistance to degradation contribute to growing environmental pollution and concerns. Enzymatic PET degradation, particularly via PETase from Ideonella sakaiensis, has emerged as a sustainable approach due to its ability to depolymerize PET under mild conditions. While research has largely focused on enhancing the enzyme's...

Topics

• Polyethylene Terephthalates
• Protein Engineering
• Hydrolases
• Burkholderiales
• Catalytic Domain
• Mutation