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Flow cytometry-based diagnosis of primary immunodeficiency diseases

3 Jul 2017

Abstract excerpt

Primary immunodeficiencies (PIDs) are a heterogeneous group of inherited diseases of the immune system. The definite diagnosis of PID is ascertained by genetic analysis; however, this takes time and is costly. Flow cytometry provides a rapid and highly sensitive tool for diagnosis of PIDs. Flow cytometry can evaluate specific cell populations and subpopulations, cell surface, intracellular and intranuclear...

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PMID: 28684198
DOI: 10.1016/j.alit.2017.06.003

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