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Article

A Practical Framework for GT-Seq Panel Optimization.

Molecular ecology resources - 1 Jul 2026

Rg Chandika, Ott-Conn Caitlin N, Euclide Peter T, Blanchong Julie A, Schmoldt Angela, DeYoung Randy W, Walsh Daniel P, Larson Wes A, Latch Emily K

Abstract excerpt

Genotyping-in-thousands by sequencing (GT-seq) panels are powerful tools in ecological, evolutionary and conservation genomics, yet the optimization process critical for robust and reproducible genotyping remains poorly formalized. Here, we present an iterative workflow for GT-seq panel optimization that emphasizes systematic refinement, quality control and structured decision-making to improve panel performance...

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Identifiers

PMID: 42360682
DOI: 10.1111/1755-0998.70169
PMCID: PMC13308542

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