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Article

Survival outcomes and a prognostic nomogram in EGFR-mutant non-small cell lung cancer with leptomeningeal metastasis: a real-world cohort study.

Journal of neuro-oncology - 26 Jun 2026

Hong Yaping, Jiang Rongqi, Chen Shijie, Lu Dongzhu, Lin Jinlan, Huang Pan, Qu Jingyi, Deng Junfei, He Jingqi, Huang Yunjian, Lai Jinhuo

Abstract excerpt

PURPOSE: Leptomeningeal metastasis (LM) carries a poor prognosis in EGFR-mutant non-small cell lung cancer (NSCLC). This study aims to explore clinical features and survival outcomes and develop a nomogram for overall survival (OS) in this population. METHODS: We retrospectively enrolled 288 EGFR-mutant NSCLC patients with LM from Fujian Cancer Hospital (January 2019-March 2024). Prognostic variables were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42360664
DOI: 10.1007/s11060-026-05677-2

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EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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