Article
HPV Status and Genotype Associations with Nodal Involvement and Treatment Strategy in Bulgarian Patients with Head and Neck Squamous Cell Carcinoma: A Prospective Multicenter Observational Study.
Medicina (Kaunas, Lithuania) - 25 May 2026
Deliverska Elitsa, Raykova Vessela, Neichev Deyan, Yordanov Stanislav, Markov Daniel, Slavkov Svetoslav, Aleksandrova Maria, Lenkov Viktor, Pashova-Tasseva Zdravka
Abstract excerpt
Background and Objectives: Head and neck squamous cell carcinoma (HNSCC) is a biologically heterogeneous malignancy with variable clinical behavior and prognosis. Human papillomavirus (HPV)-associated tumors represent a distinct subgroup; however, data from Eastern European populations remain limited. This study aimed to evaluate the association between HPV DNA status and nodal involvement in a Bulgarian HNSCC...
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