HPV DNA genotyping, HPV E6*I mRNA detection, and p16INK4a/Ki-67 staining in Belgian head and neck cancer patient specimens, collected within the HPV-AHEAD study.

doi:10.1016/j.canep.2021.101925

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HPV DNA genotyping, HPV E6*I mRNA detection, and p16INK4a/Ki-67 staining in Belgian head and neck cancer patient specimens, collected within the HPV-AHEAD study.

Cancer epidemiology - 1 Jun 2021

Simoens Cindy, Gorbaslieva Ivana, Gheit Tarik, Holzinger Dana, Lucas Eric, Ridder Ruediger, Rehm Susanne, Vermeulen Peter, Lammens Martin, Vanderveken Olivier M, Kumar Rekha Vijay, Gangane Nitin, Caniglia Alessandro, Maffini Fausto, Rubio Maria Belén Lloveras, Anantharaman Devasena, Chiocca Susanna, Brennan Paul, Pillai Madhavan Radhakrishna, Sankaranarayanan Rengaswamy, Bogers Johannes, Pawlita Michael, Tommasino Massimo, Arbyn Marc

Abstract excerpt

BACKGROUND: The main risk factors for head and neck cancer (HNC) are tobacco and alcohol use. However, an important fraction of oropharyngeal cancer (OPC) is caused by human papillomaviruses (HPV), a subgroup with increasing incidence in several western countries. METHODS: As part of the HPV-AHEAD study, we assessed the role of HPV infection in 772 archived tissue specimens of Belgian HNC patients: 455 laryngeal...

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PMID: 33839457
DOI: 10.1016/j.canep.2021.101925

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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