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Article

Causal associations between mitochondrial DNA copy number and gastrointestinal diseases: A Mendelian randomization study.

Medicine - 19 Jun 2026

Wang Zheng, Yang Zhiliang, Zhou Yun

Abstract excerpt

We conducted a Mendelian randomization (MR) study to examine the associations of mitochondrial DNA copy number (mtDNA-cn) with 27 gastrointestinal diseases (GDs). To investigate the causal relationship between mtDNA-cn and the risk of 27 GDs, a two-sample MR analytic framework was used. A series of quality-control procedures were followed in order to select eligible instrumental variables that were strongly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42332533
DOI: 10.1097/MD.0000000000049417
PMCID: PMC13286426

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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