Expression of miR-155, miR-223, miR-29b, miR-142-3p, and miR-142-5p in kidney allografts with acute tubular necrosis, rejection phenotypes, and BK-polyomavirus nephropathy.

Abstract excerpt

Specific tissue microRNA (miRNA) profiles may reflect biologically relevant pathways of kidney allograft injury and rejection. We analyzed the intragraft expression of five preselected miRNAs (miR-29b-3p, miR-142-3p, miR-142-5p, miR-155-5p and miR-223-3p) using qPCR in biopsies from patients with antibody-mediated rejection (ABMR; n = 26), T cell-mediated rejection (TCMR; n = 14), BK polyomavirus nephropathy...

Topics

• Humans
• MicroRNAs
• Kidney Transplantation
• Female
• Graft Rejection
• Male