Article
Porcine MutBERT: a family of lightweight genomic foundation models for functional element prediction in pigs.
Briefings in bioinformatics - 4 May 2026
Long Weicai, Zhou Rong, Wei Wenkang, Zhang Xiaoai, Wu Shanshan, Li Kui, Zhang Yanlin, Wang Zishuai
Abstract excerpt
The pig (Sus scrofa) is both an economically important livestock species and a valuable biomedical model . Its genome bears regulatory features shaped by domestication and selection that are often poorly captured by genomic language models (gLMs) trained on human or model organism data. To address these challenges, we developed Porcine MutBERT, a suite of lightweight gLMs with 86 million parameters that employs a...
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