Radiomics using contrast-enhanced T1-weighted imaging and clinical features for predicting response to EGFR-TKIs in EGFR-mutated non-small cell lung cancer patients with brain metastases.

Abstract excerpt

OBJECTIVES: To construct and validate a model based on clinical characteristics and magnetic resonance imaging (MRI) radiomics to predict 1-year efficacy of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) in patients with EGFR-mutant non-small cell lung cancer (NSCLC) brain metastases (BMs). METHODS: This study retrospectively analyzed data from 338 patients with EGFR-mutant NSCLC BMs from...

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