Article
Brain-Tumor Interface-Based MRI Radiomics Models to Determine EGFR Mutation, Response to EGFR-TKI and T790M Resistance Mutation in Non-Small Cell Lung Carcinoma Brain Metastasis.
Journal of magnetic resonance imaging : JMRI - 1 Dec 2023
Fan Ying, Wang Xinti, Yang Chunna, Chen Huanhuan, Wang Huan, Wang Xiaoyu, Hou Shaoping, Wang Lihua, Luo Yahong, Sha Xianzheng, Yang Huazhe, Yu Tao, Jiang Xiran
Abstract excerpt
BACKGROUND: Preoperative assessment of epidermal growth factor receptor (EGFR) status, response to EGFR-tyrosine kinase inhibitors (TKI) and development of T790M mutation in non-small cell lung carcinoma (NSCLC) patients with brain metastases (BM) is important for clinical decision-making, while previous studies were only based on the whole BM. PURPOSE: To investigate values of brain-to-tumor interface (BTI) for...
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