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Article

Putamen function and MAOA genotype define genetic and neural subtypes of hyperactivity-impulsivity in ADHD.

Journal of affective disorders - 1 Nov 2026

Feng Yuan, Gao Yuan, Liu Qianrong, Zhu Yu, Dang Chen, Wu Guisen, Zhong Shaogen, Shi Naizhen, Lin Xindi, Zhu Ziqing, Ju Changxi, Zhang Huiyi, Sui Jing, Liu Lu, Sun Li

Abstract excerpt

BACKGROUND: Hyperactivity-impulsivity (HI) is a core ADHD symptom associated with the monoamine oxidase A (MAOA) gene. The neurobiological mechanisms underlying HI heterogeneity in children carrying the MAOA risk genotype remain unclear and may involve distinct subtypes. METHODS: A total of 326 children with ADHD were genotyped for MAOA, including 108 non-risk and 218 risk carriers. Semi-supervised clustering of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42285531
DOI: 10.1016/j.jad.2026.122127

Genes

MAOA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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