IL-6 (-174 G/C) and IL-10 (-1082 G/A) polymorphisms and serum levels in Sudanese patients with end-stage renal disease and overt hepatitis B infection: a pilot comparative study.

doi:10.1186/s12865-026-00854-4

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Article

IL-6 (-174 G/C) and IL-10 (-1082 G/A) polymorphisms and serum levels in Sudanese patients with end-stage renal disease and overt hepatitis B infection: a pilot comparative study.

BMC immunology - 11 Jun 2026

Shmed Omer Boshra Mohamedsalih, Hussein Waleed Abdelateif

Abstract excerpt

BACKGROUND: Patients with end-stage renal disease (ESRD) undergoing maintenance hemodialysis are at increased risk for persistent hepatitis B virus (HBV) infection. Host immunogenetic variations, particularly in cytokines regulating pro- and anti-inflammatory responses, may influence viral chronicity. This study evaluated the association of IL-6 - 174G/C and IL-10 - 1082G/A polymorphisms and their corresponding...

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PMID: 42277653
DOI: 10.1186/s12865-026-00854-4
PMCID: PMC13523524

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