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Article

Autophagy-Mitophagy Pathway-Linked Genetic Variants Associate with Systemic Inflammation and Interact with Dietary Factors in Asian and European Cohorts.

International journal of molecular sciences - 27 Mar 2026

Choi Youngjin, Park Sunmin

Abstract excerpt

Autophagy-mitophagy pathways are essential for regulating immune homeostasis. However, their contribution to population-level chronic low-grade systemic inflammation (SI) remains unclear. The objective was to investigate the association between variation in the genes related to the autophagy-mitophagy pathways and SI, and to examine whether lifestyle factors modify this relationship. We conducted genome-wide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41977248
DOI: 10.3390/ijms27073062
PMCID: PMC13072760

Genes

SI
VPS33A
AP3S1
ATG12
ATG16L1
ATG7
BECN1
INPP5D
OPTN
RAB7A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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