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Article

Peritransplant molecular MRD monitoring by targeted NGS in patients with FLT3-ITD-mutated acute myeloid leukemia.

Blood advances - 25 Aug 2026

Hu Xiaoxia, Zhao Yeqian, Jiang Chuanhe, Fan Yamin, Shi Jimin, Luo Yi, Yu Jian, Lai Xiaoyu, Liu Lizhen, Ye Yishan, Liang Jiehan, Huang Xin, Zheng Zhongzheng, Huang He, Shi Wei, Zhao Yanmin

Abstract excerpt

ABSTRACT: Relapse is the predominant cause of treatment failure after allogeneic hematopoietic cell transplantation (HCT) in FLT3 gene internal tandem duplication (FLT3-ITD)-mutated acute myeloid leukemia (AML). Although measurable residual disease (MRD) is increasingly used for risk stratification, optimal FLT3-ITD MRD assessment, the prognostic value of peritransplant MRD dynamics, and their implications in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42263741
DOI: 10.1182/bloodadvances.2026020264
PMCID: PMC13495369

Genes

FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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