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Distinct thresholds condition sense posttranscriptional gene silencing initiation and amplification.

The Plant cell - 2 Jun 2026

Lacroix Martin, Butel Nicolas, Barrios Andana, Yu Agnès, Bouteiller Nathalie, Le Masson Ivan, Vaucheret Hervé

Abstract excerpt

It has long been known that Pro35S-driven sense transgenes have a high propensity to undergo posttranscriptional gene silencing (S-PTGS). However, what exactly conditions S-PTGS initiation and amplification to make it systemic remains unknown. Through genetic screens, we show that antagonistic chromatin-related mutations enhancing and reducing transgene expression result in enhanced and reduced S-PTGS...

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Arabidopsis
Arabidopsis Proteins
Gene Expression Regulation, Plant
Gene Silencing
Plants, Genetically Modified

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA Interference

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PMID: 42263196
DOI: 10.1093/plcell/koag166
PMCID: PMC13318159

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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