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Article

Angiotensin-Converting Enzyme 1 (ACE1) gene polymorphisms in pediatric patients with COVID-19: impact on disease severity and outcomes.

BMC medical genomics - 8 Jun 2026

Mahmoudi Shima, Hosseinpour Sadeghi Reihaneh, Pourakbari Babak, Teymuri Mostafa, Mamishi Setareh

Abstract excerpt

BACKGROUND: Angiotensin-converting enzyme 1 (ACE1) gene polymorphisms have been suggested to influence susceptibility to and severity of coronavirus disease 2019 (COVID-19) through dysregulation of the renin-angiotensin system. Despite considerable research on COVID-19, the influence of genetic factors, particularly polymorphisms in the ACE gene, on disease severity in pediatric populations remains inadequately...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42260544
DOI: 10.1186/s12920-026-02408-4
PMCID: PMC13483549

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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