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Lean, Non-Autoimmune Young-Onset Diabetes in Bangladesh: A Metabolically Obese Phenotype With Disproportionate Insulin Secretory Defect.

Endocrinology, diabetes & metabolism - 1 Jul 2026

Hasan Mashfiqul, Sultana Nusrat, Shil Kishore Kumar, Salam Sayad Bin Abdus, Ashraf Koushik, Bhuiyan Abdullah Al Noman, Al Masud Md Omor, Ratul Rifat Hossain, Hasanat Muhammad Abul

Abstract excerpt

BACKGROUND: Young-onset diabetes in South Asians frequently manifests in lean individuals, but the metabolic drivers of this phenotype remain poorlycharacterised. OBJECTIVE: This study aimed to evaluate the clinical, biochemical, and insulin-related indices of lean, non-autoimmune young-onset diabetes mellitus (DM) among Bangladeshi young adults. METHODS: This comparative cross-sectional study (2023-2024)...

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PMID: 42246549
DOI: 10.1002/edm2.70251
PMCID: PMC13238763

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