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Article

Types of genotypes in progressive familial intrahepatic cholestasis and liver transplantation: A meta-analysis of observational studies.

PloS one - 1 Jan 2026

Sakka Rania, Abroug Hela, Youssef Sabrine Ben, Mekki Mongi, M'rad Ridha

Abstract excerpt

BACKGROUND: Progressive familial intrahepatic cholestasis (PFIC) refers to a group of inherited cholestatic liver diseases that affect children, often leading to liver failure and requiring liver transplantation (LT). Many studies have established correlations between the effect of the causal gene variant types and the severity of the PFIC phenotype, the treatment considered, or its outcomes in patients....

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Identifiers

PMID: 42224341
DOI: 10.1371/journal.pone.0350508
PMCID: PMC13225629

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 11 Sept 2026.

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