Article
[Association of acute kidney injury with gut microbiota: a study integrating Mendelian randomization and real-world clinical cohort].
Zhonghua wei zhong bing ji jiu yi xue - 1 Apr 2026
Li Jiao, Lian Zhiyuan, Wang Yan, Meng Haining, Fu Fengdi, Qu Yan
Abstract excerpt
OBJECTIVE: To investigate the association between acute kidney injury (AKI) and the gut microbiota by integrating 16S sequencing analysis with mendelian randomization (MR). METHODS: 1) MR analysis: The genome-wide association study (GWAS) dataset for AKI from the FinnGen consortium and the GWAS dataset for gut microbiota composition from the Dutch Microbiome Project were selected to screen single nucleotide...
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