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Comparing whole-genome sequencing to pulsed-field gel electrophoresis for vancomycin-resistant Enterococcus faecium hospital surveillance.

Microbiology spectrum - 7 Jul 2026

Mayoral Joshua, Malczynski Michael, Ruiz Javier, Polanco Wanda, Fritz Kevin, Nunez Jovanneé, Rathod Shardul N, Kling Kendall, Qi Chao

Abstract excerpt

Vancomycin-resistant enterococci (VREs) have emerged as an important public health concern and a leading cause of healthcare-associated infections. Accurately distinguishing between closely related VRE strains is imperative for infection control measures in the setting of hospital outbreaks. Although pulsed-field gel electrophoresis (PFGE) is considered the gold standard for VRE strain typing, recent studies have...

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Identifiers

PMID: 42188592
DOI: 10.1128/spectrum.00847-26
PMCID: PMC13340300

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