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Global epidemiological insights on the antimicrobial resistance of Enterococcus faecium and a genomic analysis framework.

Microbial genomics - 1 Nov 2025

Lee Kihyun, Jang Yoon-Ha, Park Kuenyoul, Sung Heungsup, Kim Mi-Na

Abstract excerpt

Enterococcus faecium is a pathogen that frequently causes infections and outbreaks in hospitals. Despite the increasing need for genomic surveillance of E. faecium, a standardized genomic analysis framework for this pathogen is lacking. We aim to conduct a comprehensive global epidemiological overview and propose a genomic analysis framework. We analysed 21,058 public E. faecium genomes from 80 countries to...

Topics

Enterococcus faecium
Humans
Gram-Positive Bacterial Infections
Multilocus Sequence Typing
Genome, Bacterial
Polymorphism, Single Nucleotide
Anti-Bacterial Agents
Linezolid
Genomics
Drug Resistance, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genotype

Virulence

Vancomycin

Microbial Sensitivity Tests

Source

Open in PubMed Open full text

Identifiers

PMID: 41264352
DOI: 10.1099/mgen.0.001573
PMCID: PMC12633814

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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