Article
Whole-genome sequencing surveillance of vancomycin-resistant Enterococcus faecium (VRE) detects hospital outbreaks and identifies the postanesthesia care unit as a transmission locus.
Infection control and hospital epidemiology - 1 Aug 2025
Schrader Sarah M, Baker Meghan A, Rhee Chanu, Klompas Michael, Taffner Samantha, Pearson Zachary, Worley Jay, Bry Lynn, Kanjilal Sanjat, Brigl Manfred, Pecora Nicole D
Abstract excerpt
OBJECTIVE: Vancomycin-resistant enterococci (VRE) can cause serious healthcare-associated infections. Patients can become colonized and infected through contact with healthcare workers, hospital surfaces, equipment, and other patients. We evaluated the utility of broadly applied whole-genome sequencing (WGS) surveillance of vancomycin-resistant Enterococcus faecium (VREfm) for detection of hospital-based...
Topics
- Humans
- Whole Genome Sequencing
- Cross Infection
- Enterococcus faecium
- Gram-Positive Bacterial Infections
- Disease Outbreaks
- Vancomycin-Resistant Enterococci
- Retrospective Studies
- Polymorphism, Single Nucleotide