Article
Placental mitochondrial DNA mutation-related oxidative stress underlies subsequent risk of adverse prognosis in sFGR twins.
BMC pregnancy and childbirth - 23 May 2026
Huang Nana, Zhi Yun, Jiang Hai, Gong Xiaoli, Yang Jing, Wang Xueju, Li Luyao, Yuan Pengbo, Wei Yuan, Zhao Yangyu
Abstract excerpt
BACKGROUND: Selective fetal growth restriction (sFGR), a serious complication of monochorionic diamniotic (MCDA) twin pregnancies, typically results from unequal placental sharing, especially in type II sFGR. This condition is associated with an increased risk of intrauterine death and adverse neurological outcomes in one of the twin fetuses. Mitochondria play an important role in fetal development and...
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