Article
Integrating haplotype-enhanced HIV surveillance with national databases improves the resolution of transmission networks, drug resistance, and risk assessment.
Emerging microbes & infections - 1 Dec 2026
Cai Dongjun, Feng Yi, Gan Mengze, Li Huan, Wang Dong, Hao Jingjing, Lin Lu, Tang Yue, Wang Yicong, Liao Lingjie, Wang Zheng, Xing Hui
Abstract excerpt
Sanger and other consensus-based HIV surveillance methods provide limited resolution for characterizing transmission dynamics. This study evaluated the added value of integrating haplotype sequences into the division of research on viral immunology (DRVI) pol database to improve analyses of viral diversity, transmission networks, and haplotype-level drug resistance. We deep sequenced the pol gene from 95 newly...
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