Article
The Asian atopic dermatitis phenotype combines features of atopic dermatitis and psoriasis with increased TH17 polarization.
The Journal of allergy and clinical immunology - 1 Nov 2015
Noda Shinji, Suárez-Fariñas Mayte, Ungar Benjamin, Kim Soo Jung, de Guzman Strong Cristina, Xu Hui, Peng Xiangyu, Estrada Yeriel D, Nakajima Saeko, Honda Tetsuya, Shin Jung U, Lee Hemin, Krueger James G, Lee Kwang-Hoon, Kabashima Kenji, Guttman-Yassky Emma
Abstract excerpt
BACKGROUND: Atopic dermatitis (AD) shows very high prevalence in Asia, with a large unmet need for effective therapeutics. Direct comparisons between European American (EA) and Asian patients with AD are unavailable, but earlier blood studies detected increased IL-17(+)-producing cell counts in Asian patients with AD. OBJECTIVE: We sought to characterize the Asian AD skin phenotype and compare it with the EA AD...
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