PGT-A reveals triploid embryos among normally fertilized oocytes: frequency and blastocyst features.

doi:10.1007/s10815-026-03900-7

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Article

PGT-A reveals triploid embryos among normally fertilized oocytes: frequency and blastocyst features.

Journal of assisted reproduction and genetics - 1 Jul 2026

Nohales Mar, Escribá María José, Martín Ángel, Coello Aila, Insua Fernanda, Santos María José

Abstract excerpt

INTRODUCTION: With the widespread adoption of blastocyst culture and advances in genetic testing technologies enabling reliable determination of ploidy status, the traditional concept of normal fertilization is being re-evaluated. Although the presence of two pronuclei (2PN) is conventionally considered indicative of normal fertilization, not all 2PN-derived embryos are euploid. A proportion of trophectoderm (TE)...

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Identifiers

PMID: 42159835
DOI: 10.1007/s10815-026-03900-7
PMCID: PMC13518750

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.