Characterization of the first complete genome sequence of yellow fever virus (YFV) in Sierra Leone: Implications for public health.

doi:10.1371/journal.pntd.0014354

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Characterization of the first complete genome sequence of yellow fever virus (YFV) in Sierra Leone: Implications for public health.

PLoS neglected tropical diseases - 1 May 2026

Sandi John Demby, Brock-Fisher Taylor M, Kallon Tiangay Mariama Patience Sallay, Paye Marietou F, Fofanah Ibrahim Umaru, Nosamiefan Dolo, Kamara Mohamed Saio, Teh Aiah Joshua, Turay Alhaji, Wilkason Colby, Baudi Ian, Tomkins-Tinch Christopher, I'Anson Chelsea, Stachler Elyse, Pekar Jonathan E, Ozonoff Al, Park Daniel, Happi Christian, Sabeti Pardis C, Grant Donald S

Abstract excerpt

Yellow fever virus (YFV), a mosquito-borne orthoflavivirus that causes severe hemorrhagic disease, is endemic in parts of South America and Africa, yet genomic data from Sierra Leone is lacking despite ongoing case-based surveillance. Using hybrid-capture metagenomic sequencing, we generated a complete 10,611 nt YFV genome (98% coverage) from an adult male patient who reported to the Kailahun Government Hospital...

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PMID: 42149940
DOI: 10.1371/journal.pntd.0014354
PMCID: PMC13215606

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