Genetic diversity and evolutionary dynamics of Ebola virus in Sierra Leone.

doi:10.1038/nature14490

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Article

Genetic diversity and evolutionary dynamics of Ebola virus in Sierra Leone.

Nature - 6 Aug 2015

Tong Yi-Gang, Shi Wei-Feng, Liu Di, Qian Jun, Liang Long, Bo Xiao-Chen, Liu Jun, Ren Hong-Guang, Fan Hang, Ni Ming, Sun Yang, Jin Yuan, Teng Yue, Li Zhen, Kargbo David, Dafae Foday, Kanu Alex, Chen Cheng-Chao, Lan Zhi-Heng, Jiang Hui, Luo Yang, Lu Hui-Jun, Zhang Xiao-Guang, Yang Fan, Hu Yi, Cao Yu-Xi, Deng Yong-Qiang, Su Hao-Xiang, Sun Yu, Liu Wen-Sen, Wang Zhuang, Wang Cheng-Yu, Bu Zhao-Yang, Guo Zhen-Dong, Zhang Liu-Bo, Nie Wei-Min, Bai Chang-Qing, Sun Chun-Hua, An Xiao-Ping, Xu Pei-Song, Zhang Xiang-Li-Lan, Huang Yong, Mi Zhi-Qiang, Yu Dong, Yao Hong-Wu, Feng Yong, Xia Zhi-Ping, Zheng Xue-Xing, Yang Song-Tao, Lu Bing, Jiang Jia-Fu, Kargbo Brima, He Fu-Chu, Gao George F, Cao Wu-Chun

Abstract excerpt

A novel Ebola virus (EBOV) first identified in March 2014 has infected more than 25,000 people in West Africa, resulting in more than 10,000 deaths. Preliminary analyses of genome sequences of 81 EBOV collected from March to June 2014 from Guinea and Sierra Leone suggest that the 2014 EBOV originated from an independent transmission event from its natural reservoir followed by sustained human-to-human infections....

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PMID: 25970247
DOI: 10.1038/nature14490
PMCID: PMC10601608

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