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Article

Intranasal Da Chuanxiong formula alleviates vestibular migraine-like phenotypes via modulation of DRD2/TRPV1-associated signaling.

Journal of ethnopharmacology - 15 Sept 2026

Xu Handong, Tang Xuxia, Chen Sibei, Chen Jingjing, Liu Danqing, Li Bin, Nan Wenmeng, He Xiao

Abstract excerpt

ETHNOPHARMACOLOGICAL RELEVANCE: Da Chuanxiong Formula (DCXF), composed of Ligusticum chuanxiong and Gastrodia elata, is a classical traditional Chinese medicine prescription historically used for headache disorders. However, its role in vestibular migraine (VM) remains unclear. AIM OF THE STUDY: This study investigated the therapeutic effects of DCXF on VM-related phenotypes in an nitroglycerin (NTG)-induced...

Read the complete abstract on PubMed

Topics

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Share to Administration, Intranasal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drugs, Chinese Herbal

Share to Rats, Sprague-Dawley

Share to Receptors, Dopamine D2

Share to Signal Transduction

Share to TRPV Cation Channels

Source

Identifiers

PMID: 42144207
DOI: 10.1016/j.jep.2026.121871

Genes

DRD2
TRPV1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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