Recent progress in the understanding of psychological complications of acromegaly: toward a longitudinal clinical phenotype.

Abstract excerpt

Acromegaly is a chronic endocrine disorder where biochemical remission often fails to ensure psychological recovery. Drawing on cross‑sectional, longitudinal and registry evidence, this paper proposes a longitudinal clinical phenotype to reconcile divergence between hormonal control and patient‑reported outcomes. Psychological burden unfolds along a temporal gradient, where HR‑QoL captures persistent functional...

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