Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Potassium-Uptake Systems, Trk and Kdp, Coordinately Contribute to Growth Regulation and Survival of M. tuberculosis in Ion-Depleted and Acidic Environments.

International journal of molecular sciences - 29 Apr 2026

Osman Ayman G E, Matjokotja Maborwa T, Allam Mushal, Ismail Arshad, Anderson Ronald, Cholo Moloko C

Abstract excerpt

The Mycobacterium tuberculosis bacterium encodes two active potassium (K+)-uptake transport systems, the Trk and the Kdp. The Trk is the low-affinity K+ transporter, consisting of two TrkA proteins, while the Kdp consists of the high-affinity K+ transporter KdpFABC and the two-component system KdpDE. Both transporters are utilised by the bacteria for growth and survival. During growth, the bacteria utilise the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Biofilms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cation Transport Proteins

Share to Gene Expression Regulation, Bacterial

Share to Macrophages

Share to Mutation

Share to Mycobacterium tuberculosis

Share to Potassium

Source

Open in PubMed Open full text

Identifiers

PMID: 42123544
DOI: 10.3390/ijms27093962
PMCID: PMC13163235

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Potassium-Uptake Systems, Trk and Kdp, Coordinately Contribute to Growth Regulation and Survival of M. tuberculosis in Ion-Depleted and Acidic Environments.PMID 42123544Read ↗

Potassium response and homeostasis in Mycobacterium tuberculosis modulates environmental adaptation and is important for host colonizationSemantic proximity Read ↗

The KdpD/KdpE Two-Component System: Integrating K+ Homeostasis and VirulenceSemantic proximity Read ↗

Identification of trkH, encoding a potassium uptake protein required for Francisella tularensis systemic dissemination in mice.Semantic proximity Read ↗

Effects of clofazimine on potassium uptake by a Trk-deletion mutant of Mycobacterium tuberculosis.Semantic proximity Read ↗

Interaction of the sensor module of Mycobacterium tuberculosis H37Rv KdpD with members of the Lpr family.Semantic proximity Read ↗

KefB inhibits phagosomal acidification but its role is unrelated to M. tuberculosis survival in host.Semantic proximity Read ↗

Metal ion transport and regulation in mycobacterium tuberculosisSemantic proximity Read ↗

Rv0783c of <i>Mycobacterium tuberculosis</i> acts as a proton-motive force dependent multidrug efflux transporter involved in the efflux of structurally unrelated antibiotics and enhancing biofilm formationSemantic proximity Read ↗

The MprB Extracytoplasmic Domain Negatively Regulates Activation of the Mycobacterium tuberculosis MprAB Two-Component SystemSemantic proximity Read ↗

Redundant potassium transporter systems guarantee the survival of Enterococcus faecalis under stress conditionsSemantic proximity Read ↗

Two‐component sensor histidine kinases of Mycobacterium tuberculosis: Beacons for niche navigationSemantic proximity Read ↗

A Trk/HKT-type K+ transporter from Trypanosoma brucei.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.