Article
The Coexistence of Asthma and Common Variable Immunodeficiency in a Patient with TNFRSF13B Gene Mutation.
Iranian journal of allergy, asthma, and immunology - 1 Feb 2026
Ranjbarnejad Tayebeh, Salehi Mansoor, Abolhassani Hassan, Sherkat Roya, Sharifi Mohammadreza
Abstract excerpt
Common variable immunodeficiency disorder (CVID) is the most prevalent primary immunodeficiency in adults. Pathogenic mutations of the TNFRSF13B gene were identified in CVID patients and associated with autoimmunity and lymphoproliferation. A study on Swedish children unaffected by CVID has shown that rare variants in the TNFRSF13B gene increase the risk of asthma. To the best of our knowledge, asthma has not...
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