Detection of drug resistance mutations and spoligotype mapping in Mycobacterium tuberculosis using deeplex sequencing, including novel and uncharacterized spoligotypes.

Abstract excerpt

Tuberculosis (TB) remains one of the most significant infectious diseases globally, particularly affecting low- and middle-income countries, including Mexico. Its persistence is driven, among other factors, by the emergence of drug-resistant strains and the complex genetic diversity of Mycobacterium tuberculosis (M.tb). Accurate identification and molecular characterization of circulating strains are essential...

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