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Article

Gingiva-Derived Decellularised Extracellular Matrix Hydrogel Supports Osteogenic and Angiogenic Phenotypes of 3D STRO-1+ GMSC/HUVEC Spheroids In Vitro.

International dental journal - 1 Aug 2026

Liu Yushan, Zheng Xiao, Qiao Wei, Wen Shuyi, Lin Yusen, Gan Yujian, Zhao Yaqi, Chen Zhenyu, Wang Ruijie, Huang Xufeng, Rong Mingdeng

Abstract excerpt

INTRODUCTION AND AIMS: Stem cell-based bone tissue engineering is often limited by insufficient osteogenic differentiation and inadequate vascularisation, largely attributable to the absence of a biomimetic stem cell niche. This study aimed to develop a human gingiva-derived decellularised extracellular matrix hydrogel (G-dECM) as a supportive microenvironment for three-dimensional (3D) coculture spheroids of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42066492
DOI: 10.1016/j.identj.2026.109603
PMCID: PMC13144590

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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