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Activating the healing process: three-dimensional culture of stem cells in Matrigel for tissue repair

25 May 2024

Abstract excerpt

BACKGROUND: To establish a strategy for stem cell-related tissue regeneration therapy, human gingival mesenchymal stem cells (hGMSCs) were loaded with three-dimensional (3D) bioengineered Matrigel matrix scaffolds in high-cell density microtissues to promote local tissue restoration. METHODS: The biological performance and stemness of hGMSCs under 3D culture conditions were investigated by viability and...

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PMID: 38796454
DOI: 10.1186/s12896-024-00862-5

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