Article
Protocol for AI-powered classification of IDH-mutant astrocytoma using GUIDE.
STAR protocols - 19 Jun 2026
Tang Jihong, Qiao Yimeng, Ruan Yuyan, Wang Jiguang
Abstract excerpt
Accurate identification of prognostic cancer subtypes remains challenging using routine diagnostics alone. Here, we present a protocol to obtain isocitrate dehydrogenase (IDH)-mutant astrocytoma subtype predictions using the generic utility for immune/mesenchymal-enriched (IME) diagnostic estimation (GUIDE). We describe steps for preparation of image and omics inputs, setup of the GUIDE Docker container,...
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