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Article

Time-varying voriconazole clearance during extracorporeal membrane oxygenation.

Antimicrobial agents and chemotherapy - 3 Jun 2026

Yusuff Hakeem, Gadsby Jessica, Isgro Graziella, Zochios Vasileios, Jenkins David, Cooke Sarah, Mulla Hussain

Abstract excerpt

Invasive aspergillosis causes high mortality in critically ill patients, particularly those with viral pneumonitis receiving extracorporeal membrane oxygenation. Achieving effective voriconazole exposure in this setting is difficult, and existing data on drug concentrations during extracorporeal support are inconsistent. To characterize voriconazole pharmacokinetics in adults receiving extracorporeal membrane...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42059809
DOI: 10.1128/aac.00098-26
PMCID: PMC13231916

Genes

CYP2C19

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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