Article
The Role of ACE I/D Polymorphism in Glioblastoma Pathogenesis: A Study on the Turkish Population.
In vivo (Athens, Greece) - 1 Jan 2026
Türk Okan, Güvenç Yahya, Yilmaz Seda Güleç, Yaltirik Cumhur Kaan, Demirel Nail, Dağçinar Adnan, Çakir Oğuz Alp, Şanlier Nafiye, Toprak Ufuk Emre, Kurt Muhammet Teoman, Isbir Turgay
Abstract excerpt
BACKGROUND/AIM: Glioblastoma multiforme (GBM) is the most aggressive primary brain tumor, with limited survival despite standard treatments such as surgery, radiotherapy, and chemotherapy. High recurrence rates after gross total resection underline the need for identifying new therapeutic targets. Angiotensin-converting enzyme (ACE) plays a role in angiogenesis and cellular proliferation, making it a potential...
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