Genetic variants related to angiogenesis and apoptosis in patients with glioma.

doi:10.1590/0004-282X20180051

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Article

Genetic variants related to angiogenesis and apoptosis in patients with glioma.

Arquivos de neuro-psiquiatria - 1 Jun 2018

Calastri Maria Clara Jessica, Rodrigues Nicolas Luz Toledo Ortega, Hatori Gabriela, Gregório Michele Lima, Brancati Camila Ive Ferreira Oliveira, Zanovelo Eliane Milharcix, Ferraz Filho José Roberto Lopes, Neiva Cassiano Merussi, Rodrigues Junior Antonio Carlos Ponde, Godoy Moacir Fernandes de, Lancelloti Carmen Lucia Penteado, Tognola Waldir Antonio, Souza Dorotéia Rossi Silva

Abstract excerpt

BACKGROUND: Glioma, the most common primary malignant brain tumor in adults, is highly aggressive and associated with a poor prognosis. The objectives of this study were to evaluate the association of genetic polymorphisms related to angiogenesis and apoptosis with gliomas, as well as comorbidities, lifestyle, clinical profile, survival and response to treatment (temozolomide [TMZ] and radiotherapy [RT]) in...

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PMID: 29972422
DOI: 10.1590/0004-282X20180051

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