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Article

SERPINE2 Promotes Proliferation of Granulosa Cells With FecB Mutation in Small-Tailed Han Sheep by Regulating TERT.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 15 May 2026

Hou Senxuan, Liu Yufang, Wang Peng, Yang Fan, Gao Xiaoxiao, Chu Mingxing

Abstract excerpt

During follicular development, ovarian granulosa cells (GCs) proliferate to support follicle growth and endocrine function. Telomerase reverse transcriptase (TERT) contributes to telomere maintenance and is associated with the proliferative capacity of GCs. In this study, we investigated whether serine protease inhibitor E2 (SERPINE2) regulates GC function in Small-tailed Han sheep with different FecB genotypes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42048108
DOI: 10.1096/fj.202504781R

Genes

SERPINE2
TERT
CCK
ESR1
GC
PGR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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