Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Decoding the significance of TERT gene in Polycystic Ovary Syndrome: From molecular mechanisms to emerging diagnostic and therapeutic strategies.

Journal of ovarian research - 13 Mar 2026

Balgote Piyush Jagdish, Nowshad Fathima, Patnaik Avinash, Sivaraman Jayanthi

Abstract excerpt

Polycystic Ovary Syndrome (PCOS) is a complex endocrine condition affecting women of reproductive age, characterized by hyperandrogenism, anovulation, and polycystic ovary morphology. It is influenced by environmental and genetic factors with high heritability and is associated with metabolic issues such as insulin resistance (IR), chronic inflammation, and oxidative stress. Despite extensive research, the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to TERT gene
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polycystic Ovary Syndrome

Share to Telomerase

Source

Open in PubMed Open full text

Identifiers

PMID: 41827076
DOI: 10.1186/s13048-026-01972-8
PMCID: PMC13101303

Genes

TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Decoding the significance of TERT gene in Polycystic Ovary Syndrome: From molecular mechanisms to emerging diagnostic and therapeutic strategies.PMID 41827076Read ↗

Alteration of relative telomere length and telomerase reverse transcriptase expression in the granulosa cells of women during aging and assessment of in vitro fertilization outcomesSemantic proximity Read ↗

A Possible New Mechanism in the Pathophysiology of Polycystic Ovary Syndrome (PCOS): The Discovery That Leukocyte Telomere Length Is Strongly Associated With PCOSSemantic proximity Read ↗

Long non-coding RNATUG1and its molecular mechanisms in polycystic ovary syndromeSemantic proximity Read ↗

Decreased expression of TERT and telomeric proteins as human ovaries age may cause telomere shorteningSemantic proximity Read ↗

SERPINE2 Promotes Proliferation of Granulosa Cells With FecB Mutation in Small-Tailed Han Sheep by Regulating TERT.Semantic proximity Read ↗

The Ovary–Liver Axis: Molecular Science and EpidemiologySemantic proximity Read ↗

Implications of telomeres and telomerase in endometrial pathologySemantic proximity Read ↗

Telomere length and genetic variation in telomere maintenance genes in relation to ovarian cancer risk.Semantic proximity Read ↗

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer.Semantic proximity Read ↗

Association of TERT (rs2736098 and rs2736100) genetic variants with elevated risk of hepatocellular carcinoma: a retrospective case-control study.Semantic proximity Read ↗

Ovarian Telomerase and Female FertilitySemantic proximity Read ↗

Genetic variants in telomerase reverse transcriptase (TERT) and telomerase-associated protein 1 (TEP1) and the risk of male infertility.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.