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Article

Codon Usage Bias Variation and Evolutionary Signatures of Epstein-Barr Virus in Distinct Epithelial Cancers.

Viruses - 31 Mar 2026

Li Xiaoqian, Huang Xianyang, Li Wan-Ting, Baele Guy, Liu Liyuan, Li Siyan, Dai Jianjun, He Wan-Ting

Abstract excerpt

EBV genomic variation has been shown to contribute to the development of certain EBV-associated cancers. While EBV genomic variation has been extensively studied at the nucleotide level, it remains unclear how synonymous codon usage contributes to viral adaptation across epithelial cancer contexts. Here, we analyzed 1148 EBV genomes with annotated tumor origins to investigate genome-wide genetic differentiation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42043215
DOI: 10.3390/v18040425
PMCID: PMC13119708

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