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Article

Multi-omics analysis reveals AFAP1L1 as a prognostic biomarker and immune-related therapeutic target in glioma.

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences - 28 Dec 2025

Wei Chenglong, Wang Anmei, Liu Zhaoqian, Li Dai

Abstract excerpt

OBJECTIVES: Actin filament-associated protein 1 like 1 (AFAP1L1) is an adaptor protein lacking enzymatic and transcriptional activity, but the AFAP1L1 gene functions as an oncogene in colorectal cancer and gastric cancers. This study aims to investigate the role of AFAP1L1 in glioma and to explore changes in AFAP1L1 expression during glioma progression. METHODS: Clinical and transcriptomic data of glioma patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42032979
DOI: 10.11817/j.issn.1672-7347.2025.250110
PMCID: PMC12989422

Genes

AFAP1L1
CDKN2A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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