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SPrUCE: Utilizing Ultraconserved Elements of DNA for Population-Level Genetic Diversity Estimation.

Molecular ecology resources - 1 Apr 2026

Melendez Daira, Şapcı Ali Osman Berk, Bafna Vineet, Mirarab Siavash

Abstract excerpt

Ultraconserved elements (UCEs) provide ideal candidates for targeted sequencing and cost-effective acquisition of genome-wide data. While UCEs have been widely used in phylogenetic studies to reconstruct evolutionary relationships, their use in population-level research has been limited. This limited application stems from uncertainty over whether UCEs can capture the levels of genetic variation needed to answer...

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PMID: 42026820
DOI: 10.1111/1755-0998.70145
PMCID: PMC13106921

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