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Article

Estimates of genetic differentiation measured by F(ST) do not necessarily require large sample sizes when using many SNP markers.

PloS one - 1 Jan 2012

Willing Eva-Maria, Dreyer Christine, van Oosterhout Cock

Abstract excerpt

Population genetic studies provide insights into the evolutionary processes that influence the distribution of sequence variants within and among wild populations. F(ST) is among the most widely used measures for genetic differentiation and plays a central role in ecological and evolutionary genetic studies. It is commonly thought that large sample sizes are required in order to precisely infer F(ST) and that...

Topics

Alleles
Animals
Ecology
Female
Gene Frequency
Genetic Drift
Genetic Markers
Genetics, Population
Genome
Genotype
Humans
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Models, Genetic

Models, Statistical

Mutation

Polymorphism, Single Nucleotide

Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 22905157
DOI: 10.1371/journal.pone.0042649
PMCID: PMC3419229

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Estimates of genetic differentiation measured by F(ST) do not necessarily require large sample sizes when using many SNP markers.PMID 22905157Read ↗

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