Article
Vitamin D Receptor Polymorphisms and the Effect of Vitamin D Supplementation on Diabetes Risk Among Adults With Prediabetes.
JAMA network open - 1 Apr 2026
Dawson-Hughes Bess, Huggins Gordon S, Nelson Jason, Vickery Ellen, Powers Sarah N, Pittas Anastassios G
Abstract excerpt
Importance: Achieving and maintaining a serum 25-hydroxyvitamin D (25[OH]D) level of 40 ng/mL or higher, compared with 20 to 30 ng/mL, may lower diabetes risk among adults with prediabetes. It is not known whether a genetically defined subgroup is more likely to experience benefits from targeting higher 25(OH)D levels with vitamin D3 supplementation. Objective: To assess the role of common polymorphisms of the...
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